Prof. Kiyoshi Takeda graduated from Osaka University School of Medicine in 1992 and conducted his PhD work at the Graduate School of Medicine, Osaka University, under the supervision of Prof. Shizuo Akira. He was an assistant professor at Hyogo College of Medicine and Research Institute for Microbial Diseases, Osaka University, working on Toll-like receptor-dependent pathogen recognition mechanisms. In 2003, Prof. Takeda became a professor at the Medical Institute of Bioregulation, Kyushu University, and then moved to the Graduate School of Medicine, Osaka University in 2007. Now, he is a director and professor at the Immunology Frontier Research Center at Osaka University. His research activity is focused on understanding the pathogenesis of inflammatory bowel diseases, particularly the analysis of how intestinal homeostasis is maintained by mucosal immune cells and epithelial cells. Prof. Takeda also analyzes how microbiota resides in the intestine without evoking inflammatory responses and influences the host’s health.