Dr. Tsoi completed his PhD in biomedical science at the Medical University of South Carolina, supervised by Dr. W Jim Zheng. His PhD work focused on developing data integration approaches to enhance prioritization and interpretation of high throughput experimental results. Dr. Tsoi then worked as a research fellow in the Center for Statistical Genetics from the Department of Biostatistics at the University of Michigan. He has worked with Dr. Goncalo Abecasis and Dr. James T. Elder on various genetic and genomics projects for psoriasis. He joined the Department of Dermatology, Department of Computational Medicine & Bioinformatics, and the Department of Biostatistics at the University of Michigan between 2015-2016 as faculty. Dr. Tsoi is interested in investigating complex cutaneous disorders’ pathology and genetic architecture using systems biology approaches. Working with Drs. James T. Elder and Johann Gudjonsson, Dr. Tsoi’s research aims to develop analysis pipelines and computational approaches to provide biological inferences from genetics and genomics data. His work in genetic association studies revealed over 30 novel psoriasis susceptibility regions and highlighted different disease pathways. Recent studies from his lab identified molecular components shaping heterogeneity among psoriatic patients and revealed shared and unique genetic components between psoriasis and its comorbidities.
Areas of Interest
Genetics and genomics; heterogeneity comorbidities