Dr. Luigi Naldi earned a diploma in Classical Studies and a degree in Industrial Design at Scuola Politecnica di Design in Milan before moving to medicine. He graduated as a medical doctor at the University of Pavia in 1981. From 1984 to 1986, he was a junior investigator at the Laboratory of Clinical Pharmacology of the Mario Negri Institute in Milan. In 1988, he moved to the clinical arena at the Department of Dermatology of the University of Milan, Bergamo General Hospital. He qualified as a Full Professor of Dermatology in 2013. In 2017, he started a new clinical position as Director of the Department of Dermatology at the General Hospital of Vicenza. He has always considered the clinical setting as the natural laboratory for clinical research. Since 1986, he has been coordinating a collaborative research group in Italy, the Italian Group for Epidemiologic Research in Dermatology (GISED). He is a co-founder of the European Dermatoepidemiology Network (EDEN). In 2003, he established a research center at the Bergamo General Hospital, Centro Studi GISED, with the aim of promoting integrated clinical research programs in Dermatology.