International Psoriasis Council

Advancing Knowledge. Improving Care.

Advancing Knowledge. Improving Care.

Commentary: Prevalence and Factors Associated with Sleep Disturbance in Adult Patients with Psoriasis

blog_-_commentary_-_dauden-tello
dauden-tello_esteban

Esteban Dauden-Tello, MD, PhD
Department of Dermatology, Hospital Universitario de la Princesa
Madrid, Spain

PUBLICATION

1. Prevalence and Factors Associated with Sleep Disturbance in Adult Patients with Psoriasis. Sahin e, M Hawro, Weller K, et al. J Eur Acad Dermatol Venereol. 2022 May;36(5):688-697. doi: 10.1111/jdv.17917. Epub 2022 Mar 8. PMID: 35020226.

Why this article was chosen

Sleep disorders are frequently found in patients with psoriasis, but the specific factors have remained elusive and have never been studied comprehensively. This study sheds light on this, outlining the prevalence and characteristics associated with this still enigmatic aspect of psoriasis.

Commentary

Sleep disorders have a high prevalence in patients with psoriasis and significantly impact their physical and psychological well-being. The relationship between sleep disorders and psoriasis has been analyzed in numerous studies but remains poorly understood, primarily due to potential confounding factors such as pruritus, anxiety, or depression.

In this article, researchers from Berlin and Lübeck (Germany) dive deeper into understanding the impact of sleep disturbances in patients with psoriasis to identify clinical, demographic, and psychological factors. Using validated questionnaires for evaluating sleep and other measurements of quality of life, they compared psoriasis patients with a group of healthy individuals.

The significant findings of their study revealed that the prevalence of sleep disturbances was higher in psoriasis patients, and sleep was more impaired compared to healthy subjects. No association between sleep disturbance and psoriasis severity was observed, although most patients with sleep disturbances had well-controlled mild psoriasis. Other findings include observations that intense pruritus that occurred at bedtime was associated with impaired sleep (probably due to direct interference with sleep). Sleep disturbances were associated with anxiety, depression, and diminished health-related quality of life, particularly in female psoriasis patients. Increased levels of anxiety and depression were the main predictors of sleep impairment (better than pruritus parameters altogether).

The limitation of the current study includes the inability to define a causal relationship between sleep disturbances and their associated factors. However, it does not detract from the merits of this study that helps us better understand sleep disorders in patients with psoriasis, raising the possibility that complementary psychotherapy aimed at reducing anxiety, depression, and psychological distress may help to improve sleep in our patients.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Categories

Recent Posts

New IPC Guidelines on Generalized Pustular Psoriasis

Commentary: An Oral Interleukin-23-Receptor Antagonist Peptide for Plaque Psoriasis

Introducing our Latest IPC Councilors: Experts in Psoriasis Treatment and Research

Also Read

Biological agents for psoriasis

Commentary: An Oral Interleukin-23-Receptor Antagonist Peptide for Plaque Psoriasis

This commentary provides expert analysis on recent research findings, clinical trial results, and the promising future of therapies for individuals with moderate to severe plaque psoriasis. Uncover the latest advancements in psoriasis treatments, focusing on the significant impact of new biological agents and oral IL-23 receptor antagonists.

Read More
Commentary -Tiago Torres
Clinical responses

Commentary: Single-cell and Spatial Transcriptomics Analysis of Psoriasis Skin Lesions After IL-23 Inhibition

Gain expert insights into two recent publications shedding light on the molecular mechanisms of IL-23/IL-17 axis-targeting biologic therapies for psoriasis treatment. The commentary discusses longitudinal single-cell and spatial transcriptomics analyses, revealing early drug actions and genetic factors influencing clinical responses.

Read More

Subscribe to the IPC Newsletter

Stay up-to-date on the latest research, news, and upcoming events right in your inbox.