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This educational session will explore the clinical challenges of distinguishing between psoriasis and atopic dermatitis in non-classic
presentations, including psoriasiform spongiotic dermatitis and paradoxical drug reactions induced by biologic therapies like anti
TNF or IL-17 inhibitors. Through case studies and evidence-based discussions, participants will learn how to recognize subtle
diagnostic cues and apply the latest treatment strategies, incorporating histopathology and biomarkers into their treatment
decisions. Attendees will gain practical tools to improve diagnostic confidence, optimize patient outcomes, and navigate the
therapeutic complexities of inflammatory skin disease, including mechanistic insights for managing treatment-related rashes.
LEARNING OBJECTIVES
At the conclusion of this symposium, participants will be able to:
- Analyze the diagnostic challenges of distinguishing psoriasis from atopic dermatitis in non-classic clinical
presentations, including recognition of psoriasiform spongiotic dermatitis, by identifying at least three
distinguishing clinical features. - Evaluate and apply advanced diagnostic strategies, such as histopathology and biomarker testing, to
differentiate psoriasis, atopic dermatitis, and paradoxical drug reactions, demonstrating the ability to select at
least two appropriate tools for challenging adult and pediatric cases. - Design and implement evidence-based management plans for paradoxical psoriasiform and eczematous
eruptions associated with biologic therapies, including TNF-α or IL-17 inhibitors, integrating mechanistic
insights to optimize skin-related outcomes for patients with psoriasis, atopic dermatitis, or inflammatory bowel
disease.
Agenda
Welcome from the IEC & IPC
Alan Irvine, MD, DSc, Ireland
Bruce Strober, MD, PhD, United States
Diagnostic Challenges Between Atopic Dermatitis and Psoriasis
Andrew Pink, PhD, United Kingdom
Eczematous Reactions in Patients Receiving Treatments for Psoriasis
Clinical Presentation
Jason Hawkes, MD, MS, FAAD, United States
Clinical Approach
Kenneth Gordon, MD, United States
Q & A
Moderator: Bruce Strober, MD, PhD, United States
Psoriasiform Reactions in Patients Receiving Treatments for Atopic
Dermatitis & Prurigo Nodularis
Clinical Presentation
Shawn G. Kwatra, MD, United States
Clinical Approach
Yael Anne Leshem, MD, MCR, Israel
What is Psoriasiform Spongiotic Dermatitis? Navigating
Uncertainty Using Advanced Diagnostics
Kilian Eyerich, MD, PhD, Sweden
Q & A
Moderator: Amy Paller, MS, MD, United States
Anti-TNF-a Induced Skin Eruptions in Patients with Inflammatory Bowel Disease
Presentation and Clinical Approach in Adults
Lev Pavlovsky, MD, PhD, Israel
Presentation and Clinical Approach in Children
Amy Paller, MS, MD, United States
Mechanistic Aspects of Paradoxical Reactions and Iatrogenic Switches
Johann Gudjonsson, MD, PhD, United States
Final Q & A
Moderator: Yael Anne Leshem, MD, MCR, Israel
Closing Remarks
Alan Irvine, MD, DSc, Ireland
Bruce Strober, MD, PhD, United States
Program Chairs
Amy Paller, MS, MD
Northwestern University Feinberg Medical School
Chicago, Illinois, United States
IPC Board Member
Bruce Strober, MD, PhD
Yale University and Central Connecticut Dermatology
Cromwell, Connecticut, United States
IPC President
Program Faculty
Johann Gudjonsson, MD, PhD
University of Michigan, Department of Dermatology
Ann Arbor, Michigan, United States
IPC Board Member
Jason Hawkes, MD, MS, FAAD
Oregon Medical Research Center (OMRC)
Portland, Oregon, United States
IPC Councilor
Andrew Pink, PhD
St. John’s Institute of Dermatology, Guy & St. Thomas’ NHS Foundation Trust
London, United Kingdom
IPC Councilor
This symposium is supported in part by:










